Selected articles
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Patient with synchronous metastatic colorectal cancer and multiple liver metastases – case report
06/2019 Doc. MUDr. Igor Kiss, Ph.D.; MUDr. Martin Ondrák; prof. MUDr. Zdeněk Kala, CSc.; MUDr. Vladimír Procházka, Ph.D.; prof. MUDr. Vlastimil Válek, CSc.; MUDr. Tomáš Andrašina, Ph.D.
The case report describes a case of a patient in excellent general condition, highly motivated for surgical resection of liver, in whom no metastases were recorded before, during or after liver resection. Patients with „hepatic impairment only“ generally have a better prognosis. The patient tolerated the treatment very well and could undergo several cycles of systemic treatment with minimal hematological and neurological toxicity of systemic treatment. Even in the case of relapse, a rapid and significant effect of systemic treatment has been reported.
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The case report describes a case of a patient in excellent general condition, highly motivated for surgical resection of liver, in whom no metastases were recorded before, during or after liver resection. Patients with „hepatic impairment only“ generally have a better prognosis. The patient tolerated the treatment very well and could undergo several cycles of systemic treatment with minimal hematological and neurological toxicity of systemic treatment. Even in the case of relapse, a rapid and significant effect of systemic treatment has been reported.
Treatment strategy for metastatic colorectal cancer
06/2019 Doc. MUDr. Igor Kiss, Ph.D.; prof. MUDr. Zdeněk Kala, CSc.
Colorectal cancer is the most common tumor of the digestive tract. Still a relatively large proportion of patients are diagnosed in the fourth clinical stage, i.e. the stage of metastatic disease. In the individualization of the treatment strategy, we consider a number of factors, such as the extent and dynamics of the disease, the general condition of the patient, the realistic treatment goals, and especially the patient's wishes. Although the effectiveness of systemic treatment is greatest in the early treatment lines, we can significantly prolong life of good quality in other treatment lines with current medical options.
ENTIRE ARTICLE
Colorectal cancer is the most common tumor of the digestive tract. Still a relatively large proportion of patients are diagnosed in the fourth clinical stage, i.e. the stage of metastatic disease. In the individualization of the treatment strategy, we consider a number of factors, such as the extent and dynamics of the disease, the general condition of the patient, the realistic treatment goals, and especially the patient's wishes. Although the effectiveness of systemic treatment is greatest in the early treatment lines, we can significantly prolong life of good quality in other treatment lines with current medical options.