MULTIDISCIPLINARY APPROACH to Oesophageal and gastric cancer



    This book aims at highlighting the present and very dynamic development in the field of pper GI cancers. Oesophageal and gastric cancer are diseases with poor prognosis. Looking back to ous efforts to treat these serious malignancies have been dated already to the ancient periods. The introductory chapter of this issue is therefore dedicated to history of gastric cancer that is tightly connected to history of development of surgical techniques. Surgery remains the basic cornerstone of the treatment of localized oesophageal and gastric cancer and chapters attributed to surgery delineate the sustained development either in classical surgical techniques but also an implementation of new technologies, especially robotic surgery into clinical practice.

    Price: 474 CZK (19EUR) - (40% discount),  Order: info@currentmedia.cz




Actual articles

Sternal chondrosarcoma – a case report

01/2021 MUDr. Zdeněk Chovanec, Ph.D.; MUDr. Michal Reška, Ph.D.; MUDr. Alena Berková, Ph.D.; MUDr. Vladimír Červeňák; prof. MUDr. Jiří Veselý, CSc.; MUDr. Zdeněk Dvořák, Ph.D.; MUDr. Tomáš Hanslík; MUDr. Adam Peštál, Ph.D.; MUDr. Vadym Prudius, Ph.D.; prof. MUDr. Ivan Čapov, CSc.
This case report presents the case of a 68-year-old man, who presented with slow-growing, slightly painful infiltration in the lower half of the sternum observed for two years. According to the performed computed tomography examination, a 7 * 6 * 6.5 cm infiltration of the middle part of the sternum was found. Lesion was extending 1 cm ventrally and 4 cm dorsally into the surrounding soft tissues. An open biopsy was performed with the finding of moderately differentiated (grade 2) conventional chondrosarcoma. Subsequently a multidisciplinary team composed of: the Musculoskeletal tumour committee of the Masaryk Oncology Institute in Brno, the 1st Orthopaedic Clinic of St. Anne's Faculty Hospital in Brno and the 1st Surgical Clinic of St. Anne's Faculty Hospital in Brno had referred the patient to plan and perform the surgical resection of the tumours lesion. A partial resection of the sternum with the tumor was performed, followed by reconstruction of the defect with two condensed polytetrafluoroethylene meshes using the so called „sandwich technique". Then the defect was strengthened using titanium splints and subsequently reconstructed by pectoralis major muscle flap. Definitive histology confirmed the finding of grade 2 conventional sternal chondrosarcoma.

Subsolid lung nodulus in CT imaging in a female patient with colorectal carcinoma – case report

01/2021 MUDr. Vladimír Červeňák; MUDr. Alena Berková, Ph.D.; MUDr. Zdeněk Chovanec, Ph.D.; doc. MUDr. Jiří Vaniček, Ph.D.; MUDr. Tomáš Hanslík; MUDr. Sabina Svobodová
Lung cancer is the third most common malignant process in both women and men. Lung adenocarcinoma with lepidic growth is a variant that is characterized by its proliferative growth along intact alveolar walls. More women and non-smokers tend to be affected. Early diagnosis reveals a tumor process in the non-invasive or mini-invasive stage, and the prognosis for five-year survival is around 100%. The imaging method of choice is computed tomography, where a typical image of carcinoma with lepidic growth is the subsolid nodule. Theoretical information concerning this unusual diagnosis is supplemented in the article by a clear case report of a female patient with colorectal cancer and a subsolid nodulus of the left upper pulmonary lobe, in which histological examination confirmed the diagnosis of lung adenocarcinoma with lepidic growth.

Long‑term response to sequential treatment with tyrosine kinase inhibitors in a patient with EGFR+ adenocarcinoma – case report

01/2021 MUDr. Bc. Petr Zůna
Lung cancer is one of the tumours with very bad prognosis. Patients with epidermal growth factor receptor (EGFR) positive lung cancer are treated with tyrosine kinase inhibitors with good treatment tolerance and statistically significant improved survival outcome. Case report presents long survival of the 78 years old patient with EGFR positive non-small cell lung cancer on targeted therapy.