Where is the right place for immunotherapy for advanced kidney cancer?


MUDr. Hana Študentová, Ph.D.

Onkologická klinika LF UK a FN Olomouc



Targeted therapy of renal cell carcinoma has evolved enormously during past ten years. Inhibitors of angiogenesis have dominated exclusively in the treatment algorithm until recently, when immunotherapy has become a potential rival. Immunotherapy has been going through a revival due to a different and attractive mechanism of fight against cancer. New molecules have emerged to show efficacy with a regard of response rate, improving survival outcome, however, the key question remains unanswered - what is the optimal sequence of therapy including immunotherapy in the treatment of renal cell carcinoma?



immunotherapy, renal carcinoma, checkpoint inhibitors, nivolumab, pembrolizumab



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