The story of unusual diffuse large B‑cell lymphoma – case report


Doc. MUDr. Andrea Janíková, Ph.D.

Interní hematologická a onkologická klinika LF MU a FN Brno



In the case report, we can present atypical course of primary central nervous system lymphoma (PCNSL) in the patient, who was exposed to long-term immunosuppressive therapy for idiopathic bowel disease. In the literature and in clinical practice as well, the PCNSL are thought to exclusively occur in the CNS. Our rare case brings the evidence about extracerebral systemic relapse. It is questionable, if this course is related to previous exposition to immunosuppression.


Key words

primary CNS lymphoma, immunosuppression, diffuse large B-cell lymphoma



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