Sunitinib in the treatment of neuroendocrine tumors of the gastrointestinal tract – case study

01/2019

MUDr. Dagmar Brančíková, Ph.D.

Interní hematologická a onkologická klinika LF MU a FN Brno

SUMMARY

Pheochromocytomas are rare tumors. Bilateral adrenal medullary pheochromocytomas are components of MEN- Ila and MEN Ilb (multiple endocrine neoplasia). Patient 55 years old with inoperable pheochromocytoma, with liver and abdomen cavity metastases in the time of diagnosis had high levels of adrenalin, noradrenalin and dopamin. Patient was treated by TACE, lanreotide and target therapy. The patient lives 5 years after the diagnosis of disease dissemination and 18 years after the first manifestation, with very good effect and quality of life. The case demonstrates the good effect of hormonal and anti-cancer treatment.

KEY WORDS

pheochromocytoma, multiple endocrine neoplasia, TACE, lanreotide, target therapy