Intratumoral immunotherapy

Supplementum 01/2019 Imunoterapie

RNDr. Jan Ženka, CSc.

Katedra medicínské biologie, Přírodovědecká fakulta JU, České Budějovice

SUMMARY

Intratumoral immunotherapy is based on the use of autologous tumor as a vaccine. Direct injection of small amount of immunostimulators into the tumor creates effective concentrations in situ and decreases their side effects. Our therapeutic approach amplifies the primary effect of innate immunity and creates favourable conditions for involvement of adaptive immunity.

KEY WORDS

intratumoral immunotherapy, melanoma, pancreatic adenocarcinoma