Inclusion of chemoradiotherapy to primary tumor in patient with synchronous liver metastases – case report

01/2020 Special Edition

MUDr. Marián Liberko; doc. MUDr. Renata Soumarová, Ph.D.

Radioterapeutická a onkologická klinika, 3. LF UK a FN Královské Vinohrady, Praha



Case report describes a case of patient with stenosing rectal cancer and multiple liver metastases. Systemic chemobiotherapy (mFOLFOX6 + Vectibix) led to significant response of liver metastases enabling curative surgical resection of liver metastases - liver first approach. Subsequent chemoradiotherapy of primary rectal cancer led to significant regression based on imaging methods and patient was indicated to curative surgery of rectal cancer. Combination of modalities of oncological treatment may represent in selected group of patients with metastatic colorectal cancer potentially curative approach with chance of long-term survival.


Key words

rectal cancer, liver metastases, chemotherapy, biological (targeted) therapy, radiotherapy, surgery



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