Health‑threatening interactions of phytopharmaceuticals and oncological treatment
06/2019
PharmDr. Šárka Kozáková, MBA1,2; Mgr. Vojtěch Ondra1,3; MUDr. Jana Halámková, Ph.D.4
1 Ústavní lékárna, Masarykův onkologický ústav, Brno
2 Farmakologický ústav LF MU, Brno
3 Ústav humánní farmakologie a toxikologie FaF VFU, Brno
4 Klinika komplexní onkologické péče, Masarykův onkologický ústav, Brno
SUMMARY
Around 30% of patients use food supplements and phytopharmaceuticals in potentially dangerous combinations during systemic cancer treatment. Natural substances may interfere with metabolic enzymes and transport proteins, thereby disrupting drug metabolism. In this review, we will focus on the most commonly used phytopharmaceuticals and medicinal plants, their impact on cancer treatment and the possible serious consequences that they may cause to patients.
Key words
phytopharmaceuticals, oncological treatment, interaction, medicinal plants, food supplements
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