Experience with trifluridin/tipiracil in treatment of patient with metastatic rectal cancer


MUDr. Michal Vočka

Onkologická klinika 1. LF UK a VFN, Praha



Trifluridine/tipiracil (Lonsurf), combination of trifluridine (analogue of thymidine-nucleoside) and tipiracil (thymidine phosphorylase inhibitor involved in thymidine catabolism), is one of the options for a higher-line treatment in metastatic colorectal cancer patients. The case report describes the use of this drug in the fourth line, when the disease was stabilized for 17 months without any significant side effects associated with the therapy.


Key words

colorectal cancer, palliative, trifluridin/tipiracil, survival, CNS



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