Cytoreductive surgery and hyperthermic peroperative chemotherapy in the treatment of peritoneal surfaces malignancy


Prof. MUDr. František Antoš, CSc.1,2, MUDr. Pavel Vítek, Ph.D.1, MUDr. Jiří Kopic1, MUDr. Josef Marx1, MUDr. Petr Bartoška1

1) Chirurgická klinika 1. LF UK a Nemocnice Na Bulovce, Praha

2) Chirurgická katedra IPVZ, Subkatedra koioproktoíogie IPVZ, Praha



In our countries the cytoreductive surgery + hyperthemic peroperative chemotherapy (HIPEC) is a relatively new method in the treatment of peritoneal surfaces malignancy. The 15 years experience of only one center in the Czech Republic dealing with this conditions since 1999, where more than 300 operations were performed, shows a significant benefit for patients suffering from pseudomyxoma peritonei, malignant peritoneal mesothelioma, colorectal carcinoma, ovarial epithelial cancer and primary peritoneal carcinoma. On the other hand the results in gastric cancer diagnosis were not improved. In our group of patients the lethality 7.3 % and the morbidity 6.6 % has been detected. The gradual establishment of new centers dealing with this condition is desirable.



cytoreductive surgery with hyperthermic peroperative chemotherapy, HIPEC, peritoneal malignancy



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