Axitinib treatment after rapid progression of metastatic renal cell carcinoma during sunitinib administration - case report


MUDr. Martina Spisarová

Onkologická klinika LF UP a FN Olomouc



Angiogenesis is a crucial part of process in which benign tumors become into more aggressive malignant form and also their subsequent growth and dissemination. The correlation between inhibition of VEGF receptor and its curative effect has been observed in tumors with high microvascular density for a long time. The inhibition of VEGF receptor has a huge therapeutic potential in clear cell renal carcinoma and suchlike tumors.


Key words

kidney cancer, angiogensis, axitinib, combination therapy, case report



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