Atypical chronic myeloid leukemia in patients after breast cancer treatment


MUDr. Jana Zuchnická1, MUDr. Petra Richterová1, MUDr. Zuzana Rusiňáková2, prof. MUDr. Edgar Faber, CSc.2, MUDr. Roman Hájek, CSc.1

1 Klinika hematoonkologie FN a LF OU, Ostrava

2 Hemato-onkologická klinika FN Olomouc a LF UP, Olomouc



Atypical chronic myeloid leukemia BCR/ABL1 negative is a rare disease. The prognosis is unfavorable; patients have a high risk of transformation in acute myeloid leukemia. Transplantation of allogeneic haematopoietic stem cells should therefore be considered in younger patients without significant associated illnesses for which a suitable donor has been found early in the course of disease. We use paliative treatment procedures for patients who are unsuitable for transplantation.


Key words

atypical chronic myeloid leukemia, myelodysplastic-myeloproliferative disease, granulopoiesis dysplasia, allogeneic haematopoietic stem cell transplantation



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