4D MR adaptive brachytherapy of uterine cervix carcinoma in FN Hradec Králové


MUDr. Igor Sirák, Ph.D.1; Petra Sýkorová1; Ing. Jakub Grepl1; Ing. Petr Paluska1; Šárka Kollárová1; Iva Dostálová1; Ing. Martin Kopeček2; Martina Šůnová1; Monika Sedláčková1; Ing. Linda Kašaová1; MUDr. Miroslav Hodek, Ph.D.1; MUDr. Milan Vošmik, Ph.D.1

1. Klinika onkologie a radioterapie LF UK a FN, Hradec Králové

2. Ústav biofyziky LF UK, Hradec Králové



Radiotherapy and particulary brachytherapy have been major treatment modalities for cervical cancer for over 100 years. Most of this time the brachytherapy treatment planning was based on radiographs and reference point dosimetry. Due to research of European Society for Radiotherapy and Oncology (GEC-ESTRO) a 3D brachytherapy planning, based on the magnetic resonance imaging with adaptation of the treatment to actual tumor regression in time (4D), has become a standard of care in the last decade. University hospital in Hradec Kralove is the first center in the Czech Republic to implement the adaptive brachytherapy planning of cervical carcinoma based solely on the magnetic resonance imaging for each fraction.



uterine cervix carcinoma, brachytherapy, magnetic resonance



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