Vinflunin in the treatment of metastatic urothelial carcinoma of the bladder

01/2019

MUDr. Jana Katolická, Ph.D.

Onkologicko-chirurgické oddělení, FN u svaté Anny, Brno

SUMMARY

Metastatic urothelial carcinoma is a chemotherapy sensitive disease and platinum-based chemotherapy is the standard primary treatment. Vinflunine is a third-generation antimicrotubuline agent of the vinca alkaloid class. In a randomized study a prolongation of overall survival was shown in eligible patients. The data from European studies represents the excellent experience with vinflunine in patients in daily clinical practice.

KEY WORDS

metastatic urothelial cancer, chemotherapy, vinflunine