The role of radiotherapy in the treatment of gastroesophageal junction adenocarcinoma

03/2020

MUDr. Milan Vošmik, Ph.D.

Klinika onkologie a radioterapie LF UK a FN, Hradec Králové

SUMMARY

The treatment of locally and regionally advanced gastroesophageal junction adenocarcinomas is a very controversial topic. The therapeutic approach may include preoperative chemoradiotherapy, which is commonly used in esophageal cancer, as well as perioperative chemotherapy, eventually postoperative chemoradiotherapy, which are treatment alternatives used in gastric cancer. Due to the non-uniform approach in the treatment of gastroesophageal junction tumors, the benefit of radiotherapy is not clearly defined in these tumors, although it seems that the addition of radiation may be associated with some benefit over chemotherapy alone.

Key words

adenocarcinoma of the esophagogastric junction, therapy, radiotherapy, chemotherapy