Does non‑specific immunotherapy have a place in modern oncology treatment?

Supplementum 01/2019 Imunoterapie

Doc. MUDr. Tomáš Büchler, Ph.D.

Onkologická klinika 1. LF UK a Thomayerovy nemocnice, Praha

SUMMARY

The aim of non-specific anti-tumour immunotherapy is to activate innate immunity and enhance adaptive immune responses without targeting specific antigens or a specific receptor. Cytokines were the major class of agents used as non-specific immunotherapy in the treatment of malignancies. Currently, non-specific immunotherapy is used as an adjunct to other types of immune therapies in oncology.

KEYWORDS

immunotherapy, cytokines, vaccination, Bacillus Calmette-Guérin