Selected articles

Articles for label Tomášek Jiří are displayed.. Show all articles

A patient with metastatic colorectal cancer who prefers outpatient treatment - case report

01/2020 MUDr. Jiří Tomášek, Ph.D.
We present a case report of a 75-year-old woman who has been treated for 4.5 years for metastatic colorectal cancer and emphasizes out-patient treatment, which should not significantly affect her life.
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Chemotherapy and targeted treatment in metastatic colorectal cancer

06/2017 MUDr. Jiří Tomášek, Ph.D.
Approximately 40 % of patients with colorectal cancer will develop metastatic disease. Survival of patients with metastatic colorectal cancer has improved with the introduction of targeted therapies. Survival has also improved with utilization of molecular parameters (oncogens RAS, BRAF) and other factors such as sidedness of the primary tumor. The basics of intensive chemotherapy are regimens based on oxaliplatin and irinotecan. Targeted treatment increases the effectiveness of chemotherapy. A multidisciplinary approach to treatment is needed. In brief, we describe the basic strategy of systemic treatment in metastatic colorectal cancer
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