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Long‑term treatment of metastatic urothelial carcinoma of the renal pelvis – case report
03/2021 MUDr. Michaela Barjaková; MUDr. Robert Novák; MUDr. Jana Katolická, Ph.D.; doc. MUDr. Jiří Vaniček, Ph.D.
Urothelial tumors of the upper urinary tract make up only about 5% of the urothelial tumors. In the treatment of metastatic disease, we use chemotherapeutic regimens based on a platinum derivative, as in urothelial bladder cancer. Following failure of a platinum derivative, vinflunine or taxanes (especially paclitaxel) may be given from chemotherapy in case of good performance status.
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Urothelial tumors of the upper urinary tract make up only about 5% of the urothelial tumors. In the treatment of metastatic disease, we use chemotherapeutic regimens based on a platinum derivative, as in urothelial bladder cancer. Following failure of a platinum derivative, vinflunine or taxanes (especially paclitaxel) may be given from chemotherapy in case of good performance status.
Epithelial tumors of the thymus and diagnostic options
05/2020 MUDr. Vladimír Červeňák, MUDr. Zdeněk Chovanec, Ph.D., MUDr. Alena Berková, Ph.D., doc. MUDr. Jiří Vaníček, Ph.D., MUDr. Tomáš Hanslík, MUDr. Sabina Svobodová, MUDr. Robert Novák
Epithelial tumors are the most common tumors of the thymus. This group of tumors includes thymomas and thymic carcinoma and these tumors are very rare, although they are among the most common tumors of the anterior mediastinum in adults. The thymus is an organ of the immune system that can be routinely monitored by various chest examination methods. We encounter it more in children, but it is no exception in adults either. The problem in adults is its variable appearance, as it goes through the process of involution. Involution is support by the corticosteroids during excessive stress. Likewise, these conditions can change its shape and size. The basics of embryology, anatomy together with knowledge of imaging methods, are a necessary condition for accurate diagnosis of benign and malignant thyroid tumors. Only the correct identification of these pathologies allows you to choose the appropriate method of therapy.
ENTIRE ARTICLE
Epithelial tumors are the most common tumors of the thymus. This group of tumors includes thymomas and thymic carcinoma and these tumors are very rare, although they are among the most common tumors of the anterior mediastinum in adults. The thymus is an organ of the immune system that can be routinely monitored by various chest examination methods. We encounter it more in children, but it is no exception in adults either. The problem in adults is its variable appearance, as it goes through the process of involution. Involution is support by the corticosteroids during excessive stress. Likewise, these conditions can change its shape and size. The basics of embryology, anatomy together with knowledge of imaging methods, are a necessary condition for accurate diagnosis of benign and malignant thyroid tumors. Only the correct identification of these pathologies allows you to choose the appropriate method of therapy.
Achieving complete remission after sequential treatment with docetaxel‑cabazitaxel enzalutamide in a patient with metastatic castration‑resistant pros
03/2019 MUDr. Robert Novák; MUDr. Jana Katolická, Ph.D.; MUDr. Jiří Vašina
In our case report, we present a case of a patient initially with locally-regionally advanced prostate cancer. The complete remission was achieved after sequential treatment of docetaxel-cabazitaxel-enzalutamide, with maintaining good quality of life.
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In our case report, we present a case of a patient initially with locally-regionally advanced prostate cancer. The complete remission was achieved after sequential treatment of docetaxel-cabazitaxel-enzalutamide, with maintaining good quality of life.
The case of long‑term response with good quality of life at the patient with cholangiocellular carcinoma
01/2019 MUDr. Robert Novák; MUDr. Jana Katolická, Ph.D.; MUDr. Vladimír Červeňák
Cholangiocarcinoma is a disease with poor prognosis with 5-year survival 5-15%. In our case report we are presenting the case of long term response of pacient with intrahepatic cholangicarcinoma, after complete resection, with repeated recurrencies, after repeated surgical inetrventions and administrations of chemotherapy.
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Cholangiocarcinoma is a disease with poor prognosis with 5-year survival 5-15%. In our case report we are presenting the case of long term response of pacient with intrahepatic cholangicarcinoma, after complete resection, with repeated recurrencies, after repeated surgical inetrventions and administrations of chemotherapy.