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Articles for label Maňásek Viktor are displayed.. Show all articles
Biosimilar of pegfilgrastim
01/2020 MUDr. Viktor Maňásek
Chemotherapy-induced neutropenia, and in particular febrile neutropenia, is a serious complication of antitumor systemic therapy. It is possible to indicate the growth factors of myelopoiesis in prophylaxis of neutropenia in specific situations. In addition to filgrastim and pegfilgrastim, a number of biosimillar products have recently been developed with a similar therapeutic and safety profile as compared to the original products. Biosimillar drugs are subject to the same approval processes and the same standards of pharmaceutical quality, safety and efficacy that apply to all biological drugs approved in the European Union. Reducing the cost of biosimilar preparations could optimize the use of growth factors with better availability for indicated patients.
ENTIRE ARTICLE
Chemotherapy-induced neutropenia, and in particular febrile neutropenia, is a serious complication of antitumor systemic therapy. It is possible to indicate the growth factors of myelopoiesis in prophylaxis of neutropenia in specific situations. In addition to filgrastim and pegfilgrastim, a number of biosimillar products have recently been developed with a similar therapeutic and safety profile as compared to the original products. Biosimillar drugs are subject to the same approval processes and the same standards of pharmaceutical quality, safety and efficacy that apply to all biological drugs approved in the European Union. Reducing the cost of biosimilar preparations could optimize the use of growth factors with better availability for indicated patients.
Nutritional therapy in cancer patients
06/2017 MUDr. Viktor Maňásek
Tumor diseases are posed a significant risk of developing malnutrition. Nutritional therapy is an essential part of a comprehensive treatment strategy for malignancies. We have enough valid data supporting the meaningfulness of nutritional support to improve the clinical condition of patients and compliance with the treatment plan. The presence of active tumor causes the development of varied metabolic and humoral changes, interfering with the intake and processing of the individual nutrition components. This article summarizes the current view of nutritional intervention options in the conditions of the Czech Republic, including an overview of enteral and parenteral nutrition focusing on indication in various clinical situations.
ENTIRE ARTICLE
Tumor diseases are posed a significant risk of developing malnutrition. Nutritional therapy is an essential part of a comprehensive treatment strategy for malignancies. We have enough valid data supporting the meaningfulness of nutritional support to improve the clinical condition of patients and compliance with the treatment plan. The presence of active tumor causes the development of varied metabolic and humoral changes, interfering with the intake and processing of the individual nutrition components. This article summarizes the current view of nutritional intervention options in the conditions of the Czech Republic, including an overview of enteral and parenteral nutrition focusing on indication in various clinical situations.