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Articles for label Kubecová Martina are displayed.. Show all articles

BRCA‑positive ovarian cancer – case report

05/2021 MUDr. Klaudia Regináčová; doc. MUDr. Martina Kubecová, Ph.D.
In our case report we present a patient with BRCA-positive ovarian cancer, who was diagnosed with stage IV and underwent treatment modalities which were accessible. In the case report, we wanted to emphasize the importance of a multidisciplinary team, the need for genetic testing in treatment decisions, as well as the impact of antiangiogenic and targeted treatment on the patienťs survival in a good quality of life.
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BRCA‑positive ovarian cancer – case report

06/2020 MUDr. Klaudia Regináčová; doc. MUDr. Martina Kubecová, Ph.D.
In our case report we present a patient with BRCA-positive ovarian cancer, who was diagnosed with stage IV and underwent treatment modalities which were accessible. In the case report, we wanted to emphasize the importance of a multidisciplinary team, the need for genetic testing in treatment decisions, as well as the impact of antiangiogenic and targeted treatment on the patienťs survival in a good quality of life.
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The importance of a multidisciplinary approach to the treatment of ovarian cancer and its effect on prolonging overall survival – case reports

06/2020 Doc. MUDr. Martina Kubecová, Ph.D.; MUDr. Klaudia Regináčová
Using the example of patients with advanced ovarian cancer, we try to demonstrate the importance of a multidisciplinary approach to this disease and its effect on prolonging survival.
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Trifluridine/tipiracil therapy with long‑term effect in the patient with primarily metastatic colorectal cancer – case report

03/2020 Doc. MUDr. Martina Kubecová, Ph.D.
A 71-year-old physician-surgeon in excellent condition, working full-time, with multiple locally advanced colon cancer and synchronous metastatic liver disease, was treated with subtotal colectomy and microwave ablation of liver lesions in 2015. Subsequent systemic therapy was difficult to tolerate, bevacizumab monotherapy only. He was treated with radiotherapy for progression in the liver 2016. Further progression in the liver in 2017 was solved by systemic therapy (irinotecan, cetuximab). For further progression in liver in February 2018, we have used trifluridine/tipiracil therapy, which the patient is still on (February 2020 - 28th cycle). Process stabilization with excellent tolerance has been achieved. The patient is without any problems, still working full-time.
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Breast cancer metastases to ovaries – does exist rules for diagnosis and treatment?

04/2018 MUDr. Klaudia Regináčová, doc. MUDr. Martina Kubecová, Ph.D.
Breast cancer metastases to ovaries occur either in advanced, metastatic disease. In daily practice distinguish between primary and secondary ovarian tumours is often difficult. Ultrasound is irreplaceable in diagnosis. Definitive answer often gives surgery and histological findings.
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