Early diagnosis and current treatment options for basal cell carcinoma

03/2018

MUDr. Yvetta Vantuchová, Ph.D.

Kožní oddělení FN a LF OU, Ostrava

SUMMARY

Basal cell carcinoma is the most common carcinoma with low malignant potential and mortality, and in early diagnosis with high curability. It occurs in different clinical forms, histological variants with different risk. Early diagnostics, based on experience, good clinical knowledge and histological variants, is a prerequisite for choosing the optimal modal treatment of both primary and recurrent treatment. Dominant surgery is the only surgical procedure in which contraindication can be done with non-surgical methods, radiation therapy, cryodestruction, photodynamic therapy or topical treatment. For advanced or metastatic basal cell carcinoma, vismodegib the first inhibitor hedgehog signaling pathway is used.

KEY WORDS

basal cell carcinoma, histological variants, clinical manifestations, treatment